400 µm Acid Washed Silica Beads, 200 gm 

400 µm Silica Beads are ideal for disrupting yeast (e.g., Saccharomyces, Schizosaccharomyces, etc.) in lysing tubes. Smaller beads, used for bacteria, lack the mass needed to crack open yeast, thus 400 micron glass beads are used.  The effectiveness of 400 micron silica beads can easily be monitored by microscopically examining yeast cells following bead beating.  Disrupted yeast cells appear as dark shadows (ghost yeast).  Though designed for yeast, these beads have found wide application in research ranging from phase separation to protein folding to mammalian cell differentiation (see Citations).